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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PXN All Species: 28.79
Human Site: S19 Identified Species: 52.78
UniProt: P49023 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P49023 NP_001074324.1 591 64533 S19 E S T T S H I S K R P V F L S
Chimpanzee Pan troglodytes XP_001159942 589 64154 S17 E S T T S H I S K R P V F L S
Rhesus Macaque Macaca mulatta XP_001085795 563 61555 S25 E S T T S H I S K R P V F L S
Dog Lupus familis XP_543425 664 72715 S30 E S T T S H I S K R P V F L S
Cat Felis silvestris
Mouse Mus musculus Q8VI36 591 64458 S19 E S T T S H I S K R P V F L S
Rat Rattus norvegicus Q66H76 586 64001 S19 E S T T S H I S K R P V F L S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P49024 559 61224 S19 E S T T S H I S K R P V F L T
Frog Xenopus laevis Q2TCH4 506 55983
Zebra Danio Brachydanio rerio Q6P7E4 419 45574
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_523601 581 64668 L15 S S F H S S P L S D C F K V G
Honey Bee Apis mellifera XP_624308 559 62451 S17 D L Q N T V S S E G N H V G S
Nematode Worm Caenorhab. elegans Q09476 413 46434
Sea Urchin Strong. purpuratus XP_780574 695 76058 K19 D N T R I Q L K E N R D R N I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 92.5 83.1 N.A. 93.7 74.9 N.A. N.A. 84.7 41.2 21.6 N.A. 43.1 43.3 33.8 43.4
Protein Similarity: 100 99.1 92.8 85.2 N.A. 95.7 78.3 N.A. N.A. 88.4 54.3 36.5 N.A. 54.8 57 47 56.2
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. N.A. 93.3 0 0 N.A. 13.3 13.3 0 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 100 0 0 N.A. 20 33.3 0 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % C
% Asp: 16 0 0 0 0 0 0 0 0 8 0 8 0 0 0 % D
% Glu: 54 0 0 0 0 0 0 0 16 0 0 0 0 0 0 % E
% Phe: 0 0 8 0 0 0 0 0 0 0 0 8 54 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 8 0 0 0 8 8 % G
% His: 0 0 0 8 0 54 0 0 0 0 0 8 0 0 0 % H
% Ile: 0 0 0 0 8 0 54 0 0 0 0 0 0 0 8 % I
% Lys: 0 0 0 0 0 0 0 8 54 0 0 0 8 0 0 % K
% Leu: 0 8 0 0 0 0 8 8 0 0 0 0 0 54 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 0 8 0 0 0 0 0 8 8 0 0 8 0 % N
% Pro: 0 0 0 0 0 0 8 0 0 0 54 0 0 0 0 % P
% Gln: 0 0 8 0 0 8 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 8 0 0 0 0 0 54 8 0 8 0 0 % R
% Ser: 8 62 0 0 62 8 8 62 8 0 0 0 0 0 54 % S
% Thr: 0 0 62 54 8 0 0 0 0 0 0 0 0 0 8 % T
% Val: 0 0 0 0 0 8 0 0 0 0 0 54 8 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _